Covid-19: Severe complications during pregnancy are more common in unvaccinated women, study finds

Covid-19：研究发现，未接种疫苗的孕妇在妊娠期更容易面临各种严重并发症。

Unvaccinated women accounted for 77% of SARS-CoV-2 infections that have occurred during pregnancy in Scotland and 98% of infections that led to a critical care admission, a study has found.1

一项研究发现，苏格兰未接种疫苗的孕妇在妊娠期感染新冠肺炎的比例为77%，送入重症监护的比例为98%。

Researchers looked at 4950 confirmed infections in pregnant women from 1 December 2020—when routine SARS-CoV-2 testing of maternity admissions began—which were spread relatively evenly throughout pregnancy (1543 in the first trimester, 1850 in the second, and 1557 in the third).

研究人员观察了自2020年12月1日始确诊的4950例孕妇，也是在这一天，住院产妇开始进行新冠肺炎的常规检测。这些病例在整个妊娠期间分布相对均匀（妊娠第一期出现1543例，第二期出现1850例，第三期出现1557例）。

They found that “severe complications,” such as critical care admission, stillbirths, and early neonatal deaths, were more common in those who were unvaccinated compared with those who were vaccinated.

研究人员发现，与接种疫苗的孕妇相比，未接种疫苗的孕妇更容易接受重症监护、发生死产和早期新生儿死亡等“严重并发症”。

Commenting on the study, Asma Khalil, professor of obstetrics and maternal fetal medicine at St George’s University of London, said, “The study shows that the overwhelming majority of pregnant women and babies becoming unwell or dying as a result of covid-19 were unvaccinated. The pandemic is far from over and with tens of thousands of covid-19 cases still being reported in the UK every day, it is paramount that pregnant women continue to take up the offer of a vaccine.”

阿斯玛·哈利勒（Asma Khalil）是伦敦大学圣乔治学院产科学和母胎医学的一名教授。她是这样评论这项研究的：“该项研究表明，绝大多数因新冠肺炎而身体不适或死亡的孕妇和婴儿都未接种疫苗。疫情远未结束，英国每天仍会报道数万确诊病例，因此孕妇继续接种疫苗至关重要。“

Compared with non-pregnant women of reproductive age, pregnant women with SARS-CoV-2 infection are more likely to be admitted to critical care, receive invasive ventilation and extracorporeal membrane oxygenation, and die.2 Covid-19 during pregnancy has also been associated with an increased risk of pregnancy specific complications such as pre-eclampsia, preterm birth, and stillbirth.3

与育龄未孕妇女相比，确诊孕妇更有可能接受重症监护、有创通气、体外膜肺氧合以及死亡。妊娠期感染新冠肺炎还与先兆子痫，早产和死产等特定妊娠并发症的风险增加有关。